Symbol
Name
ID

Fen1
flap structure specific endonuclease 1
MGI:102779

Phenotype annotations related to cellular

Darker colors indicate more annotations

Mouse Phenotypes

aneuploidy

abnormal telomere morphology

abnormal cell physiology

increased sensitivity to induced cell death

increased cellular sensitivity to methylmethanesulfonate

increased cellular sensitivity to gamma-irradiation

increased kidney apoptosis

increased lung apoptosis

decreased fibroblast proliferation

decreased cell proliferation

abnormal fibroblast physiology

abnormal DNA repair

abnormal double-strand DNA break repair

decreased DNA replication

chromosomal instability

spontaneous chromosome breakage

Availability

Mouse Genotype

Fen1^tm1Bhsh/Fen1^tm1Bhsh

Fen1^tm1Klng/Fen1^tm1Klng

Fen1^tm2.1Bhsh/Fen1^tm2.1Bhsh

Fen1^tm2Klng/Fen1^tm2Klng

Fen1^tm3.1Bhsh/Fen1^tm3.1Bhsh

Fen1^tm3Klng/Fen1^tm3Klng

Fen1^tm2.1Bhsh/Fen1⁺

Fen1^tm3.1Bhsh/Fen1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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