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Symbol Name ID |
Tbx3
T-box 3 MGI:98495 |
| Darker colors indicate more annotations |
| Human Phenotypes | Ventricular septal defect |
Arrhythmia |
| Disease(s) Associated with TBX3 | ||
| ulnar-mammary syndrome |
| Mouse Phenotypes | abnormal retina vasculature morphology |
abnormal retina blood vessel morphology |
abnormal vitelline vasculature morphology |
absent vitelline blood vessels |
abnormal inferior vena cava morphology |
abnormal sinoatrial node morphology |
decreased sinoatrial node size |
sinoatrial node hypoplasia |
abnormal cardiovascular development |
abnormal heart development |
abnormal fetal atrioventricular canal morphology |
abnormal heart looping |
delayed heart looping |
failure of heart looping |
ventricular septal defect |
pericardial edema |
eye hemorrhage |
increased cardiac muscle contractility |
abnormal sinus arrhythmia |
increased heart rate variability |
decreased heart rate |
sinus bradycardia |
irregular heartbeat |
abnormal impulse conducting system conduction |
absent PR interval |
shortened PR interval |
atrioventricular block |
abnormal P wave |
absent P wave |
abnormal QRS complex |
prolonged QRS complex duration |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Tbx3tm1.1(cre)Vmc/Tbx3tm1.1(cre)Vmc | ||||||||||||||||||||||||||||||||
| Tbx3tm1.1Moon/Tbx3tm1.1Moon | ||||||||||||||||||||||||||||||||
| Tbx3tm1Jcib/Tbx3tm1Jcib | ||||||||||||||||||||||||||||||||
| Tbx3tm1Pa/Tbx3tm1Pa | ||||||||||||||||||||||||||||||||
| Tbx3tm2.1Moon/Tbx3tm2.1Moon | ||||||||||||||||||||||||||||||||
| Tbx3tm3.2Moon/Tbx3tm3.2Moon | ||||||||||||||||||||||||||||||||
| Tbx3em1(IMPC)Mbp/Tbx3+ | ||||||||||||||||||||||||||||||||
| Tbx3tm1.1Moon/Tbx3+ | ||||||||||||||||||||||||||||||||
| Tbx3tm1.1Moon/Tbx3tm2Moon | ||||||||||||||||||||||||||||||||
| Tbx3tm2Moon/Tbx3+ | ||||||||||||||||||||||||||||||||
| Tbx3tm3.1Moon/Tbx3tm3.1Moon Tg(GATA6-cre)#Jbeb/0 (conditional) |
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| Tbx3tm3.1Moon/Tbx3tm3.1Moon Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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| Tbx3tm3.1Moon/Tbx3tm3.1Moon Tg(Mef2c-cre)2Blk/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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