Symbol
Name
ID

Sox4
SRY (sex determining region Y)-box 4
MGI:98366

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Ventricular septal defect
Disease(s) Associated with SOX4	Ventricular septal defect
Coffin-Siris syndrome 10

Mouse Phenotypes

persistent right dorsal aorta

abnormal coronary artery morphology

abnormal retina vasculature morphology

abnormal retina blood vessel morphology

abnormal conotruncal ridge morphology

failure of conotruncal ridge closure

persistent truncus arteriosus

abnormal semilunar valve development

abnormal heart morphology

abnormal aorticopulmonary septum morphology

abnormal interventricular septum morphology

perimembraneous ventricular septal defect

thick interventricular septum

ventricular septal defect

abnormal semilunar valve morphology

abnormal blood circulation

increased heart rate

Availability

Mouse Genotype

Sox4^em1(IMPC)Mbp/Sox4^em1(IMPC)Mbp

Sox4^tm1.1Vlf/Sox4^tm1.1Vlf

Sox4^tm1Cle/Sox4^tm1Cle

Sox4^tm2Cle/Sox4^tm2Cle

Sox4^em1(IMPC)Mbp/Sox4⁺

Sox4^tm1.1Vlf/Sox4⁺

Sox4^tm1Vlf/Sox4^tm1Vlf
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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