Symbol Name ID |
Pkd1
polycystin 1, transient receptor potential channel interacting MGI:97603 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Mitral valve prolapse |
Aortic root aneurysm |
Abnormal systemic arterial morphology |
Dilatation of the cerebral artery |
Cerebral berry aneurysm |
Mitral regurgitation |
Hypertension |
Disease(s) Associated with PKD1 | |||||||
autosomal dominant polycystic kidney disease | |||||||
polycystic kidney disease 1 |
Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
aortic dissection |
aortic aneurysm |
abnormal brain vasculature morphology |
abnormal placenta vasculature |
abnormal myocardium layer morphology |
abnormal myocardial trabeculae morphology |
thick myocardium |
thin myocardium |
heart left ventricle hypertrophy |
heart right ventricle hypertrophy |
abnormal conotruncal ridge morphology |
failure of atrioventricular cushion closure |
double outlet right ventricle |
common atrioventricular valve |
atrial septal defect |
thick interventricular septum |
ventricular septal defect |
increased heart weight |
cardiac hypertrophy |
abnormal aortic valve cusp morphology |
aortic valve stenosis |
calcified aortic valve |
thick ventricular wall |
hemopericardium |
cardiac fibrosis |
dilated heart |
dystrophic cardiac calcinosis |
aneurysm |
increased cardiac output |
increased cardiac stroke volume |
hemorrhage |
subarachnoid hemorrhage |
increased cardiac muscle contractility |
hypertension |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||
Pkd1b2b1585Clo/Pkd1b2b1585Clo | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Djmp/Pkd1tm1Djmp | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Ggg/Pkd1tm1Ggg | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Hung/Pkd1tm1Hung | * | ||||||||||||||||||||||||||||||||||||
Pkd1tm1Jzh/Pkd1tm1Jzh | * | ||||||||||||||||||||||||||||||||||||
Pkd1tm1Maa/Pkd1tm1Maa | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Rsa/Pkd1tm1Rsa | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Shh/Pkd1tm1Shh | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Som/Pkd1tm1Som | * | ||||||||||||||||||||||||||||||||||||
Pkd1tm2.1Ggg/Pkd1tm2.1Ggg | |||||||||||||||||||||||||||||||||||||
Pkd1tm2.2Bol/Pkd1tm2.2Bol | |||||||||||||||||||||||||||||||||||||
Pkd1tm3.2Bol/Pkd1tm3.2Bol | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Ggg/Pkd1tm2.1Ggg | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Shh/Pkd1tm1.1Pcha | |||||||||||||||||||||||||||||||||||||
Tg(Pkd1)6Mtru/0 | |||||||||||||||||||||||||||||||||||||
Tg(Pkd1)18Mtru/0 | |||||||||||||||||||||||||||||||||||||
Tg(Pkd1)26Mtru/0 | |||||||||||||||||||||||||||||||||||||
Pkd1tm1Ggg/Pkd1tm2Ggg Meox2tm1(cre)Sor/Meox2+ (conditional) |
* | ||||||||||||||||||||||||||||||||||||
Pkd1tm1Ggg/Pkd1tm2Ggg Tg(Tek-cre)1Ywa/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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