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Symbol
Name
ID
Nos1
nitric oxide synthase 1, neuronal
MGI:97360
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Cor pulmonale
Hepatosplenomegaly
Disease(s) Associated with NOS1
cystic fibrosis

Mouse Phenotypes
cardiovascular system phenotype
decreased susceptibility to induced choroidal neovascularization
heart left ventricle hypertrophy
decreased heart weight
abnormal cardiovascular system physiology
abnormal cerebral blood flow rate
decreased coronary flow rate
decreased cardiac muscle contractility
increased ventricle muscle contractility
abnormal cardiac muscle relaxation
abnormal heart rate
increased heart rate
abnormal response of heart to induced stress
decreased mean systemic arterial blood pressure
abnormal blood-brain barrier function
abnormal vascular wound healing
Availability Mouse Genotype
Nos1tm1Plh/Nos1tm1Plh *
Nos1tm1Plh/Nos1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory