Symbol
Name
ID

Lpl
lipoprotein lipase
MGI:96820

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Premature coronary artery atherosclerosis	Precocious atherosclerosis	Hypertension	Sudden cardiac death	Myocardial infarction	Splenomegaly	Hepatosplenomegaly	Lipemia retinalis
Disease(s) Associated with LPL	Premature coronary artery atherosclerosis	Precocious atherosclerosis	Hypertension	Sudden cardiac death	Myocardial infarction	Splenomegaly	Hepatosplenomegaly	Lipemia retinalis
coronary artery disease
familial combined hyperlipidemia
familial lipoprotein lipase deficiency

Mouse Phenotypes

abnormal capillary morphology

liver vascular congestion

abnormal lung vasculature morphology

pulmonary vascular congestion

decreased cardiac muscle triglyceride level

cardiac fibrosis

cardiac interstitial fibrosis

abnormal cardiovascular system physiology

increased cardiac muscle cell glucose uptake

decreased cardiac muscle contractility

increased left ventricle diastolic pressure

increased left ventricle systolic pressure

Availability

Mouse Genotype

Lpl^tm1Bres/Lpl^tm1Bres

Lpl^tm1Sem/Lpl^tm1Sem

Lpl^tm1Ijg/Lpl^tm1Ijg
Tg(Myh6-cre)2182Mds/? (conditional)

Lpl^tm1Ijg/Lpl^tm1Ijg
Tg(Myh6-cre)2182Mds/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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