|
Symbol Name ID |
Il10
interleukin 10 MGI:96537 |
| Darker colors indicate more annotations |
| Human Phenotypes | Gastrointestinal hemorrhage |
Hematemesis |
Melena |
Retinal hemorrhage |
Intracranial hemorrhage |
Intraventricular hemorrhage |
Joint hemorrhage |
Muscle hemorrhage |
Diffuse alveolar hemorrhage |
Localized pulmonary hemorrhage |
Bruising susceptibility |
Purpura |
Petechiae |
Spontaneous hematomas |
Conjunctivitis |
Keratoconjunctivitis sicca |
Pericarditis |
Premature coronary artery atherosclerosis |
Vasculitis |
Stroke |
Hypertension |
Raynaud phenomenon |
Sudden cardiac death |
Tachycardia |
Myocardial infarction |
Congestive heart failure |
Lymphadenopathy |
Splenic rupture |
Splenomegaly |
Hepatosplenomegaly |
Abnormal retinal vascular morphology |
Cutis marmorata |
Erythema |
Urticaria |
| Disease(s) Associated with IL10 | ||||||||||||||||||||||||||||||||||
| Behcet's disease | ||||||||||||||||||||||||||||||||||
| chronic myeloid leukemia | ||||||||||||||||||||||||||||||||||
| coronary artery disease | ||||||||||||||||||||||||||||||||||
| factor VIII deficiency | ||||||||||||||||||||||||||||||||||
| graft-versus-host disease | ||||||||||||||||||||||||||||||||||
| granulomatosis with polyangiitis | ||||||||||||||||||||||||||||||||||
| Graves' disease | ||||||||||||||||||||||||||||||||||
| lymphoplasmacytic lymphoma | ||||||||||||||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||||||||||||||
| pancreatic cancer | ||||||||||||||||||||||||||||||||||
| rheumatoid arthritis | ||||||||||||||||||||||||||||||||||
| Sjogren's syndrome | ||||||||||||||||||||||||||||||||||
| systemic lupus erythematosus | ||||||||||||||||||||||||||||||||||
| thrombocytopenia |
| Mouse Phenotypes | abnormal vascular endothelial cell morphology |
decreased susceptibility to induced choroidal neovascularization |
abnormal placental labyrinth vasculature morphology |
increased myocardial infarct size |
decreased mean systemic arterial blood pressure |
decreased vasoconstriction |
increased vasoconstriction |
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| Availability | Mouse Genotype | |||||||
| Il10tm1Cgn/Il10tm1Cgn | ||||||||
| Tg(INS-Il10)#Sar/0 | ||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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