Symbol
Name
ID

Hras
Harvey rat sarcoma virus oncogene
MGI:96224

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Atrial septal defect	Ventricular septal defect	Mitral valve prolapse	Hypertrophic cardiomyopathy	Coarctation of aorta	Lymphangiectasis	Pulmonic stenosis	Arrhythmia	Hemangioma	Cavernous hemangioma
Disease(s) Associated with HRAS	Atrial septal defect	Ventricular septal defect	Mitral valve prolapse	Hypertrophic cardiomyopathy	Coarctation of aorta	Lymphangiectasis	Pulmonic stenosis	Arrhythmia	Hemangioma	Cavernous hemangioma
Costello syndrome
linear nevus sebaceous syndrome

Mouse Phenotypes

cardiovascular system phenotype

abnormal blood vessel morphology

abnormal aorta tunica media morphology

heart left ventricle hypertrophy

heart right ventricle hypertrophy

abnormal heart morphology

increased heart atrium size

enlarged aortic valve

increased heart ventricle size

cardiac fibrosis

increased systemic arterial blood pressure

hypertension

increased systemic arterial diastolic blood pressure

increased systemic arterial systolic blood pressure

Availability

Mouse Genotype

Hras^tm2Xbr/Hras^tm2Xbr

Hras^tm1Jaf/Hras⁺
Tg(CAG-cre)13Miya/0 (conditional)

Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi/0
Tg(Tek-cre)12Flv/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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