Symbol
Name
ID

Col3a1
collagen, type III, alpha 1
MGI:88453

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Internal hemorrhage

Diffuse alveolar hemorrhage

Recurrent intrapulmonary hemorrhage

Bruising susceptibility

Ecchymosis

Abnormal cardiovascular system morphology

Abnormal heart valve morphology

Mitral valve prolapse

Ascending aortic dissection

Aortic aneurysm

Ascending tubular aorta aneurysm

Aortic dissection

Descending aortic dissection

Pulmonary artery aneurysm

Carotid cavernous fistula

Dilatation of the cerebral artery

Arterial dissection

Arterial stenosis

Arteriovenous fistulas of celiac and mesenteric vessels

Varicose veins

Arteriovenous fistula

Peripheral arteriovenous fistula

Vascular dilatation

Transient ischemic attack

Hypertension

Renovascular hypertension

Arterial rupture

Telangiectasia of the skin

Disease(s) Associated with COL3A1

Ehlers-Danlos syndrome hypermobility type

vascular type Ehlers-Danlos syndrome

Mouse Phenotypes		cardiovascular system phenotype	abnormal blood vessel morphology	abnormal aorta wall morphology	abnormal aorta elastic tissue morphology	abnormal aorta smooth muscle morphology	aortic dissection	abnormal subendocardium layer morphology	increased systemic arterial systolic blood pressure	increased vasoconstriction
Availability	Mouse Genotype	cardiovascular system phenotype	abnormal blood vessel morphology	abnormal aorta wall morphology	abnormal aorta elastic tissue morphology	abnormal aorta smooth muscle morphology	aortic dissection	abnormal subendocardium layer morphology	increased systemic arterial systolic blood pressure	increased vasoconstriction
	Col3a1^tm1Jae/Col3a1^tm1Jae	*
	Col3a1^m1Lsmi/Col3a1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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