Symbol Name ID |
Ace
angiotensin I converting enzyme MGI:87874 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Purpura |
Keratoconjunctivitis sicca |
Ventricular septal hypertrophy |
Left ventricular hypertrophy |
Mitral valve prolapse |
Pericarditis |
Premature coronary artery atherosclerosis |
Vasculitis |
Stroke |
Transient ischemic attack |
Abnormal cardiac ventricular function |
Mitral regurgitation |
Elevated diastolic blood pressure |
Elevated systolic blood pressure |
Hypertension |
Portal hypertension |
Raynaud phenomenon |
Arrhythmia |
Sudden cardiac death |
Ventricular tachycardia |
Heart block |
Myocardial infarction |
Angina pectoris |
Congestive heart failure |
Abnormality of the hepatic vasculature |
Abnormal lymph node morphology |
Lymphadenopathy |
Splenomegaly |
Hepatosplenomegaly |
Angiokeratoma |
Angiokeratoma corporis diffusum |
Erythema |
Disease(s) Associated with ACE | ||||||||||||||||||||||||||||||||
Behcet's disease | ||||||||||||||||||||||||||||||||
cerebral infarction | ||||||||||||||||||||||||||||||||
coronary artery disease | ||||||||||||||||||||||||||||||||
Fabry disease | ||||||||||||||||||||||||||||||||
familial Mediterranean fever | ||||||||||||||||||||||||||||||||
IgA glomerulonephritis | ||||||||||||||||||||||||||||||||
mitral valve prolapse | ||||||||||||||||||||||||||||||||
multiple myeloma | ||||||||||||||||||||||||||||||||
pre-eclampsia | ||||||||||||||||||||||||||||||||
sarcoidosis |
Mouse Phenotypes | cardiovascular system phenotype |
abnormal kidney arterial blood vessel morphology |
abnormal renal artery morphology |
abnormal kidney vasculature morphology |
increased heart atrium size |
increased heart weight |
dilated heart |
abnormal cardiovascular system physiology |
increased heart rate |
atrial fibrillation |
abnormal systemic arterial blood pressure |
decreased systemic arterial systolic blood pressure |
hypotension |
|
Availability | Mouse Genotype | |||||||||||||
Acetm1Keb/Acetm1Keb | ||||||||||||||
Acetm1Mcf/Acetm1Mcf | ||||||||||||||
Acetm1Unc/Acetm1Unc | ||||||||||||||
Acetm2Keb/Acetm2Keb | ||||||||||||||
Acetm2Unc/Acetm2Unc | ||||||||||||||
Acetm3Keb/Acetm3Keb | * | |||||||||||||
Acetm4Keb/Acetm4Keb | ||||||||||||||
Acetm7Keb/Acetm7Keb | ||||||||||||||
Acetm8.1Keb/Acetm8.1Keb | * | |||||||||||||
Acetm8Keb/Acetm8Keb | ||||||||||||||
Acetm9Keb/Acetm9Keb | ||||||||||||||
Acetm1Keb/Ace+ | * | |||||||||||||
Acetm1Unc/Ace+ | ||||||||||||||
Acetm2Keb/Ace+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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