|
Symbol Name ID |
Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta MGI:2155600 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Single umbilical artery |
Left atrial enlargement |
Atrial septal defect |
Ventricular septal defect |
Perimembranous ventricular septal defect |
Subvalvular aortic stenosis |
Biventricular hypertrophy |
Mitral atresia |
Bicuspid aortic valve |
Aortic valve atresia |
Ebstein anomaly of the tricuspid valve |
Left ventricular noncompaction |
Dilated cardiomyopathy |
Hypertrophic cardiomyopathy |
Asymmetric septal hypertrophy |
Interstitial cardiac fibrosis |
Hypoplastic left heart |
Hypoplastic aortic arch |
Coarctation of aorta |
Pulmonary artery hypoplasia |
Patent ductus arteriosus |
Reduced left ventricular ejection fraction |
Fourth heart sound |
Aortic valve stenosis |
Mitral regurgitation |
Mitral stenosis |
Tricuspid regurgitation |
Pulmonary arterial hypertension |
Elevated jugular venous pressure |
Right axis deviation |
Arrhythmia |
Sinus tachycardia |
Sudden cardiac death |
Ventricular tachycardia |
Ventricular arrhythmia |
Right bundle branch block |
Congestive heart failure |
| Disease(s) Associated with MYH7 | |||||||||||||||||||||||||||||||||||||
| autosomal dominant hyaline body myopathy | |||||||||||||||||||||||||||||||||||||
| autosomal recessive hyaline body myopathy | |||||||||||||||||||||||||||||||||||||
| dilated cardiomyopathy 1S | |||||||||||||||||||||||||||||||||||||
| distal myopathy 1 | |||||||||||||||||||||||||||||||||||||
| hypertrophic cardiomyopathy 1 | |||||||||||||||||||||||||||||||||||||
| hypoplastic left heart syndrome |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal heart atrium morphology |
increased heart left atrium size |
abnormal heart left ventricle morphology |
increased heart left ventricle weight |
increased heart right ventricle weight |
abnormal cardiovascular system physiology |
decreased cardiac muscle contractility |
decreased left ventricle systolic pressure |
abnormal myocardial fiber physiology |
abnormal response to cardiac infarction |
decreased systemic arterial systolic blood pressure |
congestive heart failure |
|
| Availability | Mouse Genotype | |||||||||||||
| Myh7em1Dsr/Myh7em1Dsr | ||||||||||||||
| Tg(Myh6-Myh7)102Rbns/Tg(Myh6-Myh7)102Rbns | * | |||||||||||||
| Tg(Myh6-Myh7)137Rbns/0 | ||||||||||||||
| Tg(Myh6-Myh7)102Rbns/? | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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