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Symbol Name ID |
Mtor
mechanistic target of rapamycin kinase MGI:1928394 |
| Darker colors indicate more annotations |
| Human Phenotypes | Mitral valve prolapse |
Aortic root aneurysm |
Abnormal systemic arterial morphology |
Dilatation of the cerebral artery |
Hypertension |
| Disease(s) Associated with MTOR | |||||
| autosomal dominant polycystic kidney disease |
| Mouse Phenotypes | abnormal myocardial fiber morphology |
decreased myocardial fiber size |
increased heart atrium size |
thin interventricular septum |
enlarged heart |
decreased heart left ventricle wall thickness |
increased heart ventricle size |
cardiac interstitial fibrosis |
dilated cardiomyopathy |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
abnormal myocardial fiber physiology |
increased cardiomyocyte apoptosis |
increased response of heart to induced stress |
congestive heart failure |
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| Availability | Mouse Genotype | |||||||||||||||
| Mtortm1.1Gcon/Mtortm1.1Gcon A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/28/2024 MGI 6.13 |
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