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Symbol
Name
ID
Plce1
phospholipase C, epsilon 1
MGI:1921305
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal semilunar valve development
abnormal heart morphology
increased heart weight
enlarged heart
abnormal aortic valve commissure morphology
bicuspid aortic valve
aortic valve stenosis
thick aortic valve
thick pulmonary valve
dilated heart left ventricle
dilated heart right ventricle
decreased cardiac muscle contractility
aortic valve regurgitation
pulmonary valve regurgitation
prolonged QRS complex duration
abnormal myocardial fiber physiology
decreased response of heart to induced stress
increased response of heart to induced stress
Availability Mouse Genotype
Plce1em1(IMPC)Mbp/Plce1em1(IMPC)Mbp
Plce1tm1Avsm/Plce1tm1Avsm
Plce1tm1Tkat/Plce1tm1Tkat
Plce1tm2Avsm/Plce1tm2Avsm
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory