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Symbol
Name
ID
Nexn
nexilin
MGI:1916060
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Left ventricular hypertrophy
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
Reduced left ventricular ejection fraction
Increased left ventricular end-diastolic volume
Atrial fibrillation
Disease(s) Associated with NEXN
dilated cardiomyopathy 1CC
hypertrophic cardiomyopathy 20

Mouse Phenotypes
cardiovascular system phenotype
abnormal myocardial fiber morphology
abnormal heart morphology
increased heart weight
enlarged heart
increased heart left ventricle size
dilated heart left ventricle
cardiac fibrosis
dilated cardiomyopathy
decreased cardiac muscle contractility
abnormal heart echocardiography feature
abnormal myocardial fiber physiology
Availability Mouse Genotype
Nexnem1Chen/Nexnem1Chen
Nexntm1.1Chen/Nexntm1.1Chen
Nexntm1.1Zhh/Nexntm1.1Zhh
Nexntm2.1Chen/Nexntm2.1Chen *
Nexntm1.1Chen/Nexn+ *
Nexntm1.1Zhh/Nexn+
Nexntm1Chen/Nexntm1Chen
Tg(myl7.L-cre)1118Tmhn/0  (conditional)
Nexntm1Chen/Nexntm1Chen
Tg(Tnnt2-cre)5Blh/0  (conditional)
Nexntm1Chen/Nexntm1Chen  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory