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Symbol
Name
ID
Mto1
mitochondrial tRNA translation optimization 1
MGI:1915541
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Hypertrophic cardiomyopathy
Pericardial effusion
Cardiomegaly
Bradycardia
Disease(s) Associated with MTO1
combined oxidative phosphorylation deficiency 10

Mouse Phenotypes
decreased myocardial fiber mitochondrial DNA content
myocardial fiber degeneration
cardiac muscle necrosis
increased heart weight
dilated heart
decreased heart rate
irregular heartbeat
ventricular premature beat
atrioventricular block
decreased QRS amplitude
prolonged QRS complex duration
prolonged QT interval
sinoatrial block
cardiomyopathy
Availability Mouse Genotype
Mto1Gt(G019A03)Wrst/Mto1Gt(G019A03)Wrst

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory