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Symbol Name ID |
Lztr1
leucine-zipper-like transcriptional regulator, 1 MGI:1914113 |
| Darker colors indicate more annotations |
| Human Phenotypes | Bruising susceptibility |
Abnormal cardiovascular system morphology |
Atrial septal defect |
Patent foramen ovale |
Ventricular septal defect |
Atrioventricular canal defect |
Left ventricular hypertrophy |
Bicuspid aortic valve |
Mitral valve prolapse |
Abnormal pulmonary valve morphology |
Cardiomyopathy |
Hypertrophic cardiomyopathy |
Coarctation of aorta |
Pulmonary artery stenosis |
Patent ductus arteriosus |
Abnormal coronary artery origin |
Mitral regurgitation |
Mitral stenosis |
Pulmonic stenosis |
Abnormal EKG |
Arrhythmia |
Abnormality of the lymphatic system |
Abnormality of the spleen |
Lumbosacral hemangioma |
| Disease(s) Associated with LZTR1 | ||||||||||||||||||||||||
| Noonan syndrome | ||||||||||||||||||||||||
| Noonan syndrome 2 | ||||||||||||||||||||||||
| Noonan syndrome 10 | ||||||||||||||||||||||||
| schwannomatosis |
| Mouse Phenotypes | increased myocardial fiber size |
cardiac hypertrophy |
increased cardiac stroke volume |
decreased cardiac muscle contractility |
abnormal heart echocardiography feature |
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| Availability | Mouse Genotype | |||||
| Lztr1tm1a(EUCOMM)Wtsi/Lztr1+ | ||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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