Symbol Name ID |
Foxp1
forkhead box P1 MGI:1914004 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal heart morphology |
Pulmonary arterial hypertension |
Disease(s) Associated with FOXP1 | ||
intellectual disability-severe speech delay-mild dysmorphism syndrome |
Mouse Phenotypes | cardiovascular system phenotype |
thin ventricle myocardium compact layer |
disorganized myocardium |
abnormal cardiac outflow tract development |
conotruncal ridge hyperplasia |
persistent truncus arteriosus |
abnormal heart development |
increased atrioventricular cushion size |
double outlet right ventricle |
thick interventricular septum |
ventricular septal defect |
thick ventricular wall |
thin ventricular wall |
hemorrhage |
abnormal fetal cardiomyocyte proliferation |
increased fetal cardiomyocyte proliferation |
decreased heart rate |
irregular heartbeat |
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Availability | Mouse Genotype | ||||||||||||||||||
Foxp1tm1Eem/Foxp1tm1Eem | |||||||||||||||||||
Foxp1tm2.1Eem/Foxp1tm2.1Eem Nkx2-5tm1(cre)Rjs/Nkx2-5+ (conditional) |
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Foxp1tm2.1Eem/Foxp1tm2.1Eem Tg(Tek-cre)1Ywa/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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