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Symbol
Name
ID
Foxp1
forkhead box P1
MGI:1914004
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormal heart morphology
Pulmonary arterial hypertension
Disease(s) Associated with FOXP1
intellectual disability-severe speech delay-mild dysmorphism syndrome

Mouse Phenotypes
cardiovascular system phenotype
thin ventricle myocardium compact layer
disorganized myocardium
abnormal cardiac outflow tract development
conotruncal ridge hyperplasia
persistent truncus arteriosus
abnormal heart development
increased atrioventricular cushion size
double outlet right ventricle
thick interventricular septum
ventricular septal defect
thick ventricular wall
thin ventricular wall
hemorrhage
abnormal fetal cardiomyocyte proliferation
increased fetal cardiomyocyte proliferation
decreased heart rate
irregular heartbeat
Availability Mouse Genotype
Foxp1tm1Eem/Foxp1tm1Eem
Foxp1tm2.1Eem/Foxp1tm2.1Eem
Nkx2-5tm1(cre)Rjs/Nkx2-5+  (conditional)
Foxp1tm2.1Eem/Foxp1tm2.1Eem
Tg(Tek-cre)1Ywa/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory