|
Symbol Name ID |
Map3k7
mitogen-activated protein kinase kinase kinase 7 MGI:1346877 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Patent foramen ovale |
Bicuspid aortic valve |
Patent ductus arteriosus |
Pulmonic stenosis |
| Disease(s) Associated with MAP3K7 | ||||
| frontometaphyseal dysplasia 2 |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
abnormal pharyngeal arch artery morphology |
abnormal vascular development |
abnormal vascular regression |
decreased angiogenesis |
abnormal vitelline vasculature morphology |
abnormal vascular smooth muscle morphology |
increased cardiac muscle glycogen level |
abnormal myocardial fiber morphology |
abnormal myocardial trabeculae morphology |
thin myocardium compact layer |
abnormal ventricle papillary muscle morphology |
abnormal heart morphology |
cardiac hypertrophy |
small heart |
thin ventricular wall |
dilated heart ventricle |
pericardial edema |
abnormal cardiovascular system physiology |
hemorrhage |
shortened PR interval |
abnormal QRS complex |
prolonged QRS complex duration |
cardiomyopathy |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Map3k7Gt(XB444)Byg/Map3k7Gt(XB444)Byg | |||||||||||||||||||||||||||
| Map3k7tm1.1Mds/Map3k7tm1.1Mds | |||||||||||||||||||||||||||
| Map3k7tm1Aki/Map3k7tm1Aki Tg(Tek-cre)12Flv/0 (conditional) |
* | ||||||||||||||||||||||||||
| Tg(CAG-Map3k7*K63W)1232Mds/0 Tg(Myh6-cre)2182Mds/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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