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Symbol
Name
ID

Lrp5
low density lipoprotein receptor-related protein 5
MGI:1278315

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Vitreous hemorrhage	Abnormal cardiovascular system morphology	Ventricular septal defect	Mitral valve prolapse	Aortic root aneurysm	Abnormal systemic arterial morphology	Dilatation of the cerebral artery	Hypertension	Peripheral retinal avascularization	Peripheral retinal neovascularization	Posterior retinal neovascularization
Disease(s) Associated with LRP5	Vitreous hemorrhage	Abnormal cardiovascular system morphology	Ventricular septal defect	Mitral valve prolapse	Aortic root aneurysm	Abnormal systemic arterial morphology	Dilatation of the cerebral artery	Hypertension	Peripheral retinal avascularization	Peripheral retinal neovascularization	Posterior retinal neovascularization
autosomal dominant polycystic kidney disease
exudative vitreoretinopathy 4
neovascular inflammatory vitreoretinopathy
osteoporosis-pseudoglioma syndrome
polycystic liver disease

Mouse Phenotypes		abnormal retina vasculature morphology	abnormal retina blood vessel morphology	decreased angiogenesis	abnormal vascular plexus formation	blood vessel congestion	hemorrhage	increased vascular permeability
Availability	Mouse Genotype	abnormal retina vasculature morphology	abnormal retina blood vessel morphology	decreased angiogenesis	abnormal vascular plexus formation	blood vessel congestion	hemorrhage	increased vascular permeability
	Lrp5^em1Xjz/Lrp5^em1Xjz
	Lrp5^{Gt(OST164883)Lex}/Lrp5^{Gt(OST164883)Lex}
	Lrp5^r18/Lrp5^r18
	Lrp5^tm1Dgen/Lrp5^tm1Dgen
	Lrp5^tm1Kry/Lrp5^tm1Kry
	Lrp5^tvrm111B/Lrp5^tvrm111B

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23