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Symbol
Name
ID
Wrn
Werner syndrome RecQ like helicase
MGI:109635
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Pulmonary artery stenosis
Atherosclerosis
Abnormal cerebral vascular morphology
Hypertension
Myocardial infarction
Congestive heart failure
Telangiectasia of the skin
Disease(s) Associated with WRN
Werner syndrome

Mouse Phenotypes
abnormal cardiovascular development
bicuspid aortic valve
aortic valve stenosis
bicuspid pulmonary valve
cardiac interstitial fibrosis
increased left ventricle systolic pressure
decreased systemic arterial diastolic blood pressure
heart inflammation
Availability Mouse Genotype
Wrnb2b3121.1Clo/Wrnb2b3121.1Clo
Wrntm1Led/Wrntm1Led
Wrntm1Led/Wrn+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory