Symbol Name ID |
Zic3
zinc finger protein of the cerebellum 3 MGI:106676 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal cardiovascular system morphology |
Dextrocardia |
Situs inversus totalis |
Mesocardia |
Left atrial isomerism |
Right atrial isomerism |
Atrial septal defect |
Patent foramen ovale |
Common atrium |
Ventricular septal defect |
Atrioventricular canal defect |
Complete atrioventricular canal defect |
Unbalanced atrioventricular canal defect |
Subvalvular aortic stenosis |
Single ventricle |
Double inlet left ventricle |
Mitral atresia |
Double outlet right ventricle |
Transposition of the great arteries |
Dextrotransposition of the great arteries |
Cardiomegaly |
Hypoplastic left heart |
Right aortic arch |
Hypoplastic aortic arch |
Ascending tubular aorta aneurysm |
Coarctation of aorta |
Pulmonary artery atresia |
Partial anomalous pulmonary venous return |
Total anomalous pulmonary venous return |
Interrupted inferior vena cava with azygous continuation |
Persistent left superior vena cava |
Bilateral superior vena cava |
Left superior vena cava draining to coronary sinus |
Patent ductus arteriosus |
Mitral stenosis |
Pulmonic stenosis |
Atrial reentry tachycardia |
Asplenia |
Ectopia of the spleen |
Polysplenia |
Disease(s) Associated with ZIC3 | ||||||||||||||||||||||||||||||||||||||||
situs inversus | ||||||||||||||||||||||||||||||||||||||||
visceral heterotaxy | ||||||||||||||||||||||||||||||||||||||||
X-linked VACTERL association |
Mouse Phenotypes | abnormal cardiovascular system morphology |
interrupted aortic arch |
right aortic arch |
abnormal inferior vena cava morphology |
abnormal heart development |
abnormal heart looping |
abnormal direction of heart looping |
abnormal heart morphology |
double outlet right ventricle |
d-loop transposition of the great arteries |
atrial septal defect |
abnormal heart position or orientation |
dextrocardia |
ectopia cordis |
ventricular septal defect |
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Availability | Mouse Genotype | |||||||||||||||
Zic3Ka/Zic3Ka | ||||||||||||||||
Zic3tm1Bca/Zic3tm1Bca | ||||||||||||||||
Zic3tm1Jwb/Zic3tm1Jwb | ||||||||||||||||
Zic3tm1Bca/Zic3+ | ||||||||||||||||
Zic3Ka/Y | ||||||||||||||||
Zic3tm1Bca/Y | ||||||||||||||||
Zic3tm1Jwb/Y | ||||||||||||||||
Zic3tm2.1Jwb/Y Edil3Tg(Sox2-cre)1Amc/Edil3+ (conditional) |
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Zic3tm1.1Smwa/Y Edil3Tg(Sox2-cre)1Amc/Edil3+ (conditional) |
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Zic3tm1.1Smwa/Y Tg(T-cre)1Lwd/0 (conditional) |
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Zic3tm2.1Jwb/Y Tg(T-cre)1Lwd/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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