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Symbol Name ID |
Nrp1
neuropilin 1 MGI:106206 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Tetralogy of Fallot |
| Disease(s) Associated with NRP1 | |
| tetralogy of Fallot |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal cardiovascular system morphology |
abnormal blood vessel morphology |
abnormal dorsal aorta morphology |
abnormal pharyngeal arch artery morphology |
abnormal first pharyngeal arch artery morphology |
abnormal fourth pharyngeal arch artery morphology |
abnormal second pharyngeal arch artery morphology |
abnormal sixth pharyngeal arch artery morphology |
abnormal third pharyngeal arch artery morphology |
abnormal pulmonary artery morphology |
abnormal aortic arch and aortic arch branch attachment |
right aortic arch |
double aortic arch |
abnormal coronary artery morphology |
abnormal brain vasculature morphology |
abnormal retina vasculature morphology |
abnormal retina blood vessel morphology |
abnormal retina blood vessel pattern |
abnormal induced retina neovascularization |
abnormal vascular development |
failure of vascular branching |
decreased angiogenesis |
disorganized yolk sac vascular plexus |
vascular smooth muscle hypoplasia |
persistent truncus arteriosus |
abnormal coronary vessel morphology |
transposition of great arteries |
dilated heart atrium |
ventricular septal defect |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
| Nrp1tm1.1Cruh/Nrp1tm1.1Cruh | * | ||||||||||||||||||||||||||||||
| Nrp1tm1.1Izac/Nrp1tm1.1Izac | |||||||||||||||||||||||||||||||
| Nrp1tm1Ddg/Nrp1tm1Ddg | |||||||||||||||||||||||||||||||
| Nrp1tm1Hfu/Nrp1tm1Hfu | |||||||||||||||||||||||||||||||
| Nrp1tm2Ddg/Nrp1tm2Ddg Tg(Tek-cre)1Ywa/0 (conditional) |
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| Nrp1tm1Hfu/Nrp1tm2Ddg Tg(Tek-cre)1Ywa/0 (conditional) |
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| Nrp1tm2Ddg/Nrp1tm2.1Ddg Tg(Tek-cre)1Ywa/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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