|
Symbol Name ID |
Gpx1
glutathione peroxidase 1 MGI:104887 |
| Darker colors indicate more annotations |
| Human Phenotypes | Gastrointestinal hemorrhage |
Retinal hemorrhage |
Cerebral hemorrhage |
Bruising susceptibility |
Abnormal cardiovascular system morphology |
Abnormal endocardium morphology |
Mitral valve prolapse |
Restrictive cardiomyopathy |
Coronary artery atherosclerosis |
Premature coronary artery atherosclerosis |
Medial calcification of large arteries |
Medial calcification of medium-sized arteries |
Arterial stenosis |
Premature occlusive vascular stenosis |
Arteriosclerosis |
Atherosclerosis |
Accelerated atherosclerosis |
Vascular dilatation |
Abnormal cerebral vascular morphology |
Stroke |
Ischemic stroke |
Mitral stenosis |
Hypertension |
Renovascular hypertension |
Weak pulse |
Intermittent claudication |
Pulmonary arterial hypertension |
Sudden cardiac death |
Myocardial infarction |
Angina pectoris |
Congestive heart failure |
Abnormality of the vasculature |
Lymphadenopathy |
Abnormality of the spleen |
Splenic infarction |
Splenomegaly |
Telangiectasia of the skin |
| Disease(s) Associated with GPX1 | |||||||||||||||||||||||||||||||||||||
| coronary artery disease | |||||||||||||||||||||||||||||||||||||
| multiple myeloma | |||||||||||||||||||||||||||||||||||||
| pseudoxanthoma elasticum | |||||||||||||||||||||||||||||||||||||
| sickle cell anemia |
| Mouse Phenotypes | myocardium necrosis |
abnormal cardiovascular system physiology |
increased cardiac muscle contractility |
decreased myocardial infarct size |
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| Availability | Mouse Genotype | ||||
| Tg(Gpx1)41Dkd/0 | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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