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Symbol
Name
ID
Ednrb
endothelin receptor type B
MGI:102720
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of the pulmonary artery
Disease(s) Associated with EDNRB
Waardenburg syndrome

Mouse Phenotypes
cardiovascular system phenotype
increased cardiac output
increased cardiac muscle contractility
decreased response of heart to induced stress
increased systemic arterial blood pressure
increased mean systemic arterial blood pressure
increased systemic arterial diastolic blood pressure
increased systemic arterial systolic blood pressure
decreased vasodilation
Availability Mouse Genotype
Ednrbtm1.1Yko/Ednrbtm1.1Yko
Ednrbtm1.1Nrd/Ednrb+
Ednrbtm1Ywa/Ednrbs
Ednrbtm1Yko/Ednrbtm1Yko
Tg(AQP2-cre)2Dek/0  (conditional)
Ednrbtm1Yko/Ednrbtm1Yko
Tg(Tek-cre)1Ywa/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory