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Symbol
Name
ID
Lmnb1
lamin B1
MGI:96795
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Bowel incontinence
Pseudobulbar paralysis
Depression
Atypical behavior
Personality changes
Myalgia
Disease(s) Associated with LMNB1
adult-onset autosomal dominant demyelinating leukodystrophy

Mouse Phenotypes
behavior/neurological phenotype
increased susceptibility to pharmacologically induced seizures
abnormal spatial learning
abnormal spatial reference memory
tremors
impaired coordination
straub tail
seizures
clonic seizures
abnormal spike wave discharge
Availability Mouse Genotype
Tg(Lmnb1)1Yfu/0 *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory