|
Symbol Name ID |
Gnas
GNAS complex locus MGI:95777 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Bone pain |
Depression |
Emotional lability |
Agitation |
Laryngeal dystonia |
Chest pain |
| Disease(s) Associated with GNAS | ||||||
| ACTH-independent macronodular adrenal hyperplasia 1 | ||||||
| progressive osseous heteroplasia | ||||||
| pseudohypoparathyroidism type IB |
| Mouse Phenotypes | behavior/neurological phenotype |
decreased alcohol consumption |
impaired contextual conditioning behavior |
abnormal response to new environment |
abnormal spatial learning |
impaired spatial working memory |
abnormal eating behavior |
absent gastric milk in neonates |
increased food intake |
abnormal suckling behavior |
abnormal motor capabilities/coordination/movement |
impaired righting response |
tremors |
ataxia |
impaired balance |
weakness |
abnormal posture |
decreased locomotor activity |
increased locomotor activity |
hyperactivity |
no spontaneous movement |
|
| Availability | Mouse Genotype | |||||||||||||||||||||
| Gnastm1Gwa/Gnas+ | ||||||||||||||||||||||
| Gnastm1Kel/Gnas+ | ||||||||||||||||||||||
| Gnastm1Lsw/Gnas+ | ||||||||||||||||||||||
| Gnastm2Jop/Gnas+ | * | |||||||||||||||||||||
| Gnastm2Kel/Gnas+ | ||||||||||||||||||||||
| Gnastm3Jop/Gnas+ | * | |||||||||||||||||||||
| Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-Gnas)1593Mpke/0 |
* | |||||||||||||||||||||
| Gnastm5.1Lsw/Gnastm5.1Lsw Tg(Fabp4-cre)1Abel/0 (conditional) |
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| Gnastm5.1Lsw/Gnastm5.1Lsw H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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