Symbol
Name
ID

Drd3
dopamine receptor D3
MGI:94925

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Negativism
Disease(s) Associated with DRD3	Negativism
schizophrenia

Mouse Phenotypes

behavior/neurological phenotype

decreased alcohol consumption

abnormal behavioral response to addictive substance

enhanced behavioral response to alcohol

impaired behavioral response to morphine

increased behavioral withdrawal response

impaired conditioned place preference behavior

abnormal cued conditioning behavior

increased exploration in new environment

abnormal food intake

decreased anxiety-related response

decreased grooming behavior

abnormal reflex

decreased startle reflex

abnormal motor coordination/balance

head bobbing

abnormal locomotor activation

increased vertical activity

decreased locomotor activity

increased locomotor activity

hyperactivity

increased stereotypic behavior

Availability

Mouse Genotype

Drd3^tm1Dac/Drd3^tm1Dac

Drd3^tm1Rmw/Drd3^tm1Rmw

Drd3^tm1Stl/Drd3^tm1Stl

Drd3^tm1Dac/Drd3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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