Symbol
Name
ID

Ppp1r1b
protein phosphatase 1, regulatory inhibitor subunit 1B
MGI:94860

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Negativism
Disease(s) Associated with PPP1R1B	Negativism
schizophrenia

Mouse Phenotypes

behavior/neurological phenotype

abnormal behavior

abnormal alcohol consumption

hyperactivity elicited by ethanol administration

enhanced behavioral response to cocaine

impaired behavioral response to cocaine

impaired behavioral response to morphine

impaired behavioral response to addictive substance

impaired behavioral response to xenobiotic

impaired conditioned place preference behavior

decreased locomotor activity

hyperactivity

Availability

Mouse Genotype

Ppp1r1b^tm1Aaf/Ppp1r1b^tm1Aaf

Ppp1r1b^tm1Pggd/Ppp1r1b^tm1Pggd

Ppp1r1b^tm2Pggd/Ppp1r1b^tm2Pggd

Ppp1r1b^tm3Pggd/Ppp1r1b^tm3Pggd

Ppp1r1b^tm4Pggd/Ppp1r1b^tm4Pggd

Ppp1r1b^tm5.1Pggd/Ppp1r1b^tm5.1Pggd
Tg(Drd1-cre)EY262Gsat/0
Tg(Drd1-EGFP)X60Gsat/0 (conditional)

Ppp1r1b^tm5.1Pggd/Ppp1r1b^tm5.1Pggd
Tg(Drd2-cre)ER44Gsat/0
Tg(Drd2-EGFP)S118Gsat/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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