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Symbol
Name
ID
Cic
capicua transcriptional repressor
MGI:1918972
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Autistic behavior
Hyperactivity
Attention deficit hyperactivity disorder
Motor stereotypy
Recurrent hand flapping
Disease(s) Associated with CIC
autosomal dominant intellectual developmental disorder 45

Mouse Phenotypes
behavior/neurological phenotype
impaired contextual conditioning behavior
increased aggression towards mice
decreased anxiety-related response
abnormal response to social novelty
increased locomotor activity
hyperactivity
abnormal social investigation
Availability Mouse Genotype
CicGt(XE565)Byg/Cic+ *
Cictm1b(KOMP)Wtsi/Cic+
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Emx1tm1(cre)Krj/Emx1+  (conditional)
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Tg(Otp-cre)1Hzo/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory