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Symbol
Name
ID
Spast
spastin
MGI:1858896
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Urinary incontinence
Low back pain
Depression
Apathy
Aggressive behavior
Disinhibition
Agitation
Disease(s) Associated with SPAST
hereditary spastic paraplegia 4

Mouse Phenotypes
impaired coordination
abnormal gait
long stride length
short stride length
Availability Mouse Genotype
SpastM1Gri/SpastM1Gri
Spasttm1.1Evre/Spasttm1.1Evre
Spasttm1.1Jme/Spasttm1.1Jme
Spasttm1Jfnk/Spasttm1Jfnk
Spasttm1Jfnk/Spast+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory