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Symbol
Name
ID
Dnmt3a
DNA methyltransferase 3A
MGI:1261827
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Atypical behavior
Bipolar affective disorder
Aggressive behavior
Disease(s) Associated with DNMT3A
Tatton-Brown-Rahman syndrome

Mouse Phenotypes
decreased exploration in new environment
impaired coordination
decreased grip strength
increased grip strength
abnormal gait
decreased locomotor activity
convulsive seizures
Availability Mouse Genotype
Dnmt3atm1a(KOMP)Wtsi/Dnmt3atm1a(KOMP)Wtsi
Dnmt3atm1b(KOMP)Wtsi/Dnmt3a+
Dnmt3atm1Jae/Dnmt3atm1Jae
Tg(Nes-cre)1Atp/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory