Phenotypes associated with Gja3<tm1Scr>/Gja3<tm1Scr> Gja8<R205G>/Gja8<R205G>

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Phenotypes associated with Gja3^tm1Scr/Gja3^tm1Scr Gja8^R205G/Gja8^R205G

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Gja3^tm1Scr/Gja3^tm1Scr Gja8^R205G/Gja8^R205G	involves: 129S4/SvJae * CWD/LeAgl * SJL/J	MGI:5489762

Allelic Composition	Gja3^tm1Scr/Gja3^tm1Scr Gja8^R205G/Gja8^R205G
Genetic Background	involves: 129S4/SvJae * CWD/LeAgl * SJL/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja3^tm1Scr mutation (0 available); any Gja3 mutation (16 available)
Gja8^R205G mutation (1 available); any Gja8 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Dense nuclear cataracts in Gja8^R205G/Gja8^R205G and Gja8^R205G/Gja8^R205G Gja3^tm1Scr/Gja3^tm1Scr mice but degenerating peripheral lens fibers only in Gja8^R205G/Gja8^R205G mice

vision/eye

vision/eye phenotype ( J:195727 )

N	• mice exhibit normal lens periphery and lens fiber unlike in Gja8^Nm2249 homozygotes

nuclear cataract ( J:195727 )

• dense

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