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All mouse models of biliary tract disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | cholestasis | Abcb4tm1Bor/Abcb4tm1Bor | C.129P2-Abcb4tm1Bor | J:199949 | View | |||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:254370 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
Krastm4Tyj/Kras+ Trp53tm1Brn/Trp53tm1Brn Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholestasis | Abcb4tm1Bor/Abcb4tm1Bor | involves: 129P2/OlaHsd * FVB/N | J:175015 | View | ||||
| intrahepatic cholestasis |
Abcb4tm1Bor/Abcb4tm1Bor Portm1Wolf/Portm1Wolf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * DBA * FVB/N | J:215915 | View | ||||
| | biliary atresia | Sox17tm1Ysk/Sox17+ | B6.129S1-Sox17tm1Ysk | J:194071, J:241569 | View | |||
| Caroli syndrome | Pkhd1cyli/Pkhd1cyli | D2.Cg-(D4Mit42-D4Smh6b) Pkhd1cyli/EiJ | J:343537 | View | ||||
| cholecystitis | Abcb4tm1Bor/Abcb4tm1Bor | FVB.129P2-Abcb4tm1Bor/J | J:105357 | View | ||||
| primary sclerosing cholangitis | Abcb4tm1Bor/Abcb4tm1Bor | CAnNCrl.12P2(FVB)-Abcb4tm1Bor | J:217802 | View | ||||
| primary sclerosing cholangitis | Abcb4tm1Bor/Abcb4tm1Bor | involves: 129P2/OlaHsd * BALB/c | J:168123 | View | ||||
| | intrahepatic cholestasis |
Atp8b1tm1Nbf/Atp8b1tm1Nbf Portm1Wolf/Portm1Wolf Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:215915 | View | |||
| progressive familial intrahepatic cholestasis 4 |
Tjp1tm1.1Whun/Tjp1tm1.1Whun Tjp2tm2Whun/Tjp2tm2Whun Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * C57BL/6NTac * DBA/2 | J:306936 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | intrahepatic cholestasis | Atp8b1tm1Nbf/Atp8b1tm1Nbf | involves: 129S1/SvImJ * 129S4/SvJae | J:89817 | View | |||