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All mouse models of connective tissue cancer with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | osteosarcoma |
\Prkar1atm1.2Lsk/\Prkar1a+ \Rb1tm2Brn/\Rb1+ \Tg(Col1a1-cre)1Kry/0 \Trp53tm1Brn/\Trp53tm1Brn |
involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:234128 | View | |||
| osteosarcoma |
\Prkar1atm1.2Lsk/\Prkar1a+ \Rb1tm2Brn/\Rb1tm2Brn \Trp53tm1Brn/\Trp53tm1Brn \Tg(Col1a1-cre)1Kry/0 |
involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:234128 | View | ||||
| osteosarcoma |
\Prkar1atm1.2Lsk/\Prkar1a+ \Tg(Col1a1-cre)1Kry/0 \Trp53tm1Brn/\Trp53tm1Brn |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N | J:234128 | View | ||||
| osteosarcoma |
\Ptch1tm1Yy/\Ptch1+ \Trp53tm1Brd/\Trp53+ \Tg(BGLAP-cre)1Clem/0 |
involves: 129S7/SvEvBrd * C57BL/6 * FVB/NJ | J:214349 | View | ||||
| osteosarcoma |
\Rb1tm3Tyj/\Rb1+ \Trp53tm1Brn/\Trp53tm1Brn \Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CD-1 * FVB/N | J:136693 | View | ||||
| osteosarcoma |
\Rb1tm3Tyj/\Rb1tm3Tyj \Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 \Tg(tetO-RNAi:Trp53)ASlowe/0 |
involves: 129S4/SvJae * C57BL/6 * CD-1 | J:199542 | View | ||||
| osteosarcoma |
\Rb1tm3Tyj/\Rb1tm3Tyj \Trp53tm1Brn/\Trp53tm1Brn \Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CD-1 | J:199542 | View | ||||
| osteosarcoma |
\Rb1tm3Tyj/\Rb1tm3Tyj \Trp53tm1Brn/\Trp53tm1Brn \Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CD-1 * FVB/N | J:136693, J:318035 | View | ||||
| osteosarcoma |
\Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 \Tg(tetO-RNAi:Trp53)ASlowe/0 |
involves: C57BL/6 * CD-1 | J:199542 | View | ||||
| osteosarcoma |
\Trp53tm1Brn/\Trp53tm1Brn \Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 |
involves: 129P2/OlaHsd * C57BL/6 * CD-1 | J:199542 | View | ||||
| | liposarcoma | \Tg(Fabp4-Il22)#Ychn/0 | involves: ICR | J:176141 | View | |||
| Transgenes and Other Mutations | Kaposi's sarcoma | \Tg(Acta2-RAC1*G12V)33Pjgc/0 | involves: C57BL/6 * FVB/N | J:150015 | View | |||
| Kaposi's sarcoma | \Tg(Acta2-RAC1*G12V)33Pjgc/\Tg(Acta2-RAC1*G12V)33Pjgc | involves: C57BL/6 * FVB/N | J:150015 | View | ||||
| osteosarcoma | \Tg(Bglap2-TAg)1Rkho/0 | FVB/N-Tg(Bglap2-TAg)1Rkho | J:165282 | View | ||||
| osteosarcoma | \Tg(Bglap2-TAg)1Rkho/0 | involves: FVB/N | J:234128 | View | ||||
| Additional Complex Models | myxoid liposarcoma |
\Trp53tm1Tyj/\Trp53tm1Tyj \Tg(Prrx1-FUS/DDIT3)1Mete/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:184491 | View | |||
| synovial sarcoma | \Gt(ROSA)26Sortm1(cre/ERT)Nat/\Gt(ROSA)26Sortm3(SS18/EGFP)Mrc | involves: 129 * 129S1/Sv * 129X1/SvJ | J:147728 | View | ||||
| synovial sarcoma |
\Gt(ROSA)26Sortm2(SS18)Mrc/\Gt(ROSA)26Sortm2(SS18)Mrc \Myf5tm1(cre)Mrc/\Myf5tm1(cre)Mrc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:120967 | View | ||||
| synovial sarcoma |
\Gt(ROSA)26Sortm3(SS18/EGFP)Mrc/\Gt(ROSA)26Sortm3(SS18/EGFP)Mrc \Myf5tm1(cre)Mrc/\Myf5tm1(cre)Mrc |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:120967 | View | ||||