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Disease Ontology Browser
oocyte/zygote/embryo maturation arrest 5 (DOID:0061307)
Alliance: disease page
Synonyms: female infertility due to oocyte meiotic arrest; oocyte maturation defect 5; OOMD5; OZEMA5
Alt IDs: OMIM:617996, ORDO:488191, UMLS_CUI:C5567489
Definition: An oocyte/zygote/embryo maturation arrest that is characterized by female infertility due to inability of the oocyte to exit metaphase II, resulting in fertilization failure and that has_material_basis_in homozygous or compound heterozygous mutation in the WEE2 gene on chromosome 7q34.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory