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Disease Ontology Browser
oocyte/zygote/embryo maturation arrest 3 (DOID:0061305)
Alliance: disease page
Synonyms: female infertility due to zona pellucida defect.; oocyte maturation defect 3; OOMD3; OZEMA3
Alt IDs: OMIM:617712, ORDO:404466, UMLS_CUI:C4749433
Definition: An oocyte/zygote/embryo maturation arrest that is characterized by infertility, caused by absence of the zona pellucida that results in degeneration of oocytes and 'empty follicle syndrome' on in vitro fertilization procedures and that has_material_basis_in heterozygous mutation in the ZP3 gene on chromosome 7q11.23.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory