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Disease Ontology Browser
oocyte/zygote/embryo maturation arrest 15 (DOID:0061317)
Alliance: disease page
Synonyms: female infertility due to oocyte meiotic arrest; OZEMA15; preimplantation embryonic lethality 1; PREMBL; PREMBL1
Alt IDs: OMIM:616814, ORDO:488191, UMLS_CUI:C5567489
Definition: An oocyte/zygote/embryo maturation arrest that is characterized by severely impaired zygote formation despite ovulation proceeding normally and retrieved oocytes appearing normal that has_material_basis_in homozygous mutation in the TLE6 gene on chromosome 19p13.3.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/08/2026
MGI 6.24 		The Jackson Laboratory