diphtheria (DOID:11405)
Alliance: disease page
Synonyms: corynebacterium infection
Alt IDs: DOID:4132, MESH:D003354, UMLS_CUI:C0010153
Definition: A primary bacterial infectious disease that is characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria can be restricted to the skin. It is caused by Corynebacterium diphtheriae, an aerobic Gram-positive bacterium. Diphtheria toxin spreads through the bloodstream and can lead to potentially life-threatening complications that affect other organs of the body, such as the heart and kidneys.