hereditary spastic paraplegia 81 (DOID:0112349)
Alliance: disease page
Synonyms: autosomal recessive complex spastic paraplegia due to Kennedy pathway dysfunction; autosomal recessive complex SPG due to Kennedy pathway dysfunction; spastic paraplegia 81 autosomal recessive; SPG81
Alt IDs: OMIM:618768, ORDO:506353
Definition: A hereditary spastic paraplegia characterized by onset in infancy, delayed motor development, progressive spasticity, and other neurologic impairments that has_material_basis_in homozygous or compound heterozygous mutation in the SELENOI gene on chromosome 2p23.3.