hereditary spastic paraplegia 85 (DOID:0112345)
Alliance: disease page
Synonyms: spastic paraplegia 85 autosomal recessive; SPG85
Alt IDs: OMIM:619686
Definition: A hereditary spastic paraplegia characterized by onset of motor symptoms (e.g. spasticity and hyperreflexia of the lower limbs) in the first few years of life that has_material_basis_in homozygous or compound heterozygous mutation in the RNF170 gene on chromosome 8p11.21.