nephrotic syndrome type 21 (DOID:0112267)
Alliance: disease page
Synonyms: NPHS21
Alt IDs: OMIM:618594
Definition: A familial nephrotic syndrome characterized by onset of rapidly, progressive kidney dysfunction in the first year of life, proteinuria, and diffuse mesangial sclerosis that has_material_basis_in homozygous or compound heterozygous mutation in the AVIL gene on chromosome 12q14.1.