immunodeficiency 45 (DOID:0111994)
Alliance: disease page
Synonyms: IMD45
Alt IDs: OMIM:616669
Definition: A primary immunodeficiency disease characterized by impaired control the replication of certain viruses and failure to develop an antiviral state in response to alpha-interferon or beta-interferon that has_material_basis_in homozygous or compound heterozygous mutation in the IFNAR2 gene on chromosome 21q22.11.