split hand-foot malformation (DOID:0090020)
Alliance: disease page
Synonyms: lobster-claw deformity; split-hand deformity
Alt IDs: ICD9CM:755.58, MESH:C574275, NCI:C75000, OMIM:PS183600, ORDO:2440, UMLS_CUI:C0265554
Definition: A bone development disease characterized by malformation of the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. Some patients also have mental retardation, ectodermal and craniofacial findings, and orofacial clefting.