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Disease Ontology Browser
platelet-type bleeding disorder 21 (DOID:0061328)
Alliance: disease page
Synonyms: BDPLT21
Alt IDs: OMIM:617443, ORDO:248340, UMLS_CUI:C0032197
Definition: A blood platelet disease characterized by increased risk of bleeding resulting from a functional platelet defect. Platelets have decreased or even absent dense bodies and abnormally enlarged and fused alpha-granules, and they show defective secretion and aggregation responses to agonists and that has_material_basis_in heterozygous mutation in the FLI1 gene on chromosome 11q24.3.

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory