glucocorticoid-induced osteoporosis (DOID:0060343)
Alliance: disease page
Synonyms: steroid-induced osteoporosis
Definition: An osteoporosis caused by chronic glucocorticoid use. Glucocorticoids impair the replication, differentiation and function of osteoblasts and induce the apoptosis of mature osteoblasts and osteocytes; the also favor osteoclastogenesis leading to an increase in bone resorption.