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Gene Expression Data
Assay Details
Assay
Reference: J:391429 Bi W, et al., Cardiomyocyte-Specific bcl11b Knockout Causes Left Ventricular Noncompaction by Dysregulating pou3f2 and Titin. Int J Mol Sci. 2026 Aug 12;27(16)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8409548
Gene symbol: Tnnt2
Gene name: troponin T2, cardiac
Antibody: anti-Tnnt2 (clone RV-C2)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S1A Bcl11b f/f: postnatal adult; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: red - Tnnt2; green - Bcl11b (assay MGI:8409547).
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S1A Bcl11b f/f left , S1A Bcl11b f/f right
Specimen S1A cTnT-Cre; Bcl11b f/f: postnatal adult; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: red - Tnnt2; green - Bcl11b (assay MGI:8409547).
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S1A cTnT-Cre; Bcl11b f/f left , S1A cTnT-Cre; Bcl11b f/f right
Specimen 1F E12.5 Bcl11b f/f: embryonic day 12.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS20: ventricle cardiac muscle Present 1F Bcl11b f/f E12.5 upper , 1F Bcl11b f/f E12.5 lower
Specimen 1F E12.5 cTnT-Cre; Bcl11b f/f: embryonic day 12.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS20: ventricle cardiac muscle Present 1F cTnT-Cre E12.5 upper , 1F cTnT-Cre E12.5 lower
Specimen 1F E14.5 Bcl11b f/f: embryonic day 14.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS22: ventricle cardiac muscle Present 1F Bcl11b f/f E14.5 upper , 1F Bcl11b f/f E14.5 lower
Specimen 1F E14.5 cTnT-Cre; Bcl11b f/f: embryonic day 14.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS22: ventricle cardiac muscle Present 1F cTnT-Cre E14.5 upper , 1F cTnT-Cre E14.5 lower
Specimen 1F E16.5 Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS24: ventricle cardiac muscle Present 1F Bcl11b f/f E16.5 lower , 1F Bcl11b f/f E16.5 upper
Specimen 1F E16.5 cTnT-Cre; Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS24: ventricle cardiac muscle Present 1F cTnT-Cre E16.5 upper , 1F cTnT-Cre E16.5 lower
Specimen 1F E18.5 Bcl11b f/f: embryonic day 18.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS26: ventricle cardiac muscle Present 1F Bcl11b f/f E18.5 upper , 1F Bcl11b f/f E18.5 lower
Specimen 1F E18.5 cTnT-Cre; Bcl11b f/f: embryonic day 18.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: red - Tnnt2; green - Emcn (assay MGI:8409549).
Structure Level Pattern Image Note
TS26: ventricle cardiac muscle Present 1F cTnT-Cre E18.5 upper , 1F cTnT-Cre E18.5 lower
Specimen 2A Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: green - Tnnt2; red - Mki67 (assay MGI:8409551).
Structure Level Pattern Image Note
TS24: heart left ventricle Present 2A Bcl11b f/f right , 2A Bcl11b f/f left
Specimen 2A cTnT-Cre; Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - Mki67 (assay MGI:8409551).
Structure Level Pattern Image Note
TS24: heart left ventricle Present 2A cTnT-Cre; Bcl11b f/f right , 2A cTnT-Cre; Bcl11b f/f left
Specimen 2B Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: green - Tnnt2; red - phospho histone H3.
Structure Level Pattern Image Note
TS24: heart left ventricle Present 2B Bcl11b f/f right , 2B Bcl11b f/f left
Specimen 2B cTnT-Cre; Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - phospho histone H3.
Structure Level Pattern Image Note
TS24: heart left ventricle Present 2B cTnT-Cre; Bcl11b f/f right , 2B cTnT-Cre; Bcl11b f/f left
Specimen 2D Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: green - Tnnt2; red - TUNEL.
Structure Level Pattern Image Note
TS24: heart left ventricle Present 2D Bcl11b f/f left , 2D Bcl11b f/f right
Specimen 2D cTnT-Cre; Bcl11b: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - TUNEL.
Structure Level Pattern Image Note
TS24: heart left ventricle Present 2D cTnT-Cre; Bcl11b f/f right , 2D cTnT-Cre; Bcl11b f/f left
Specimen S4 Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: green - Tnnt2; red - Yap1 (assay MGI:8409552).
Structure Level Pattern Image Note
TS24: heart left ventricle Present S4_Bcl11b f/f right , S4_Bcl11b f/f left
Specimen S4 cTnT-Cre; Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - Yap1 (assay MGI:8409552).
Structure Level Pattern Image Note
TS24: heart left ventricle Present S4_cTnT-Cre; Bcl11b f/f left , S4_cTnT-Cre; Bcl11b f/f right
Specimen 4A Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid (more )
Note: Double labeled: green - Tnnt2; red - Pou3f2 (assay MGI:8409553).
Structure Level Pattern Image Note
TS24: heart left ventricle Present 4A Bcl11b f/f left , 4A Bcl11b f/f right
Specimen 4A cTnT-Cre; Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - Pou3f2 (assay MGI:8409553).
Structure Level Pattern Image Note
TS24: heart left ventricle Present 4A cTnT-Cre; Bcl11b f/f left , 4A cTnT-Cre; Bcl11b f/f right
Specimen 5C cTnT-Cre; Bcl11b f/f: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - phospho histone H3.
Structure Level Pattern Image Note
TS24: heart left ventricle Present 5C cTnT-Cre; Bcl11b f/f; left , 5C cTnT-Cre; Bcl11b f/f; right
Specimen 5C cTnT-Cre; Bcl11b f/f; Pou3f2+/-: embryonic day 16.5; Bcl11btm1.1Leid/Bcl11btm1.1Leid, Pou3f2em1Shgjn/Pou3f2+, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - phospho histone H3.
Structure Level Pattern Image Note
TS24: heart left ventricle Present 5C cTnT-Cre; Bcl11b f/f; Pou3f2+/- left , 5C cTnT-Cre; Bcl11b f/f; Pou3f2+/- right
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory