Hnf1b Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:279716 Braitsch CM, et al., LATS1/2 suppress NFkappaB and aberrant EMT initiation to permit pancreatic progenitor differentiation. PLoS Biol. 2019 Jul;17(7):e3000382
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8351667
Gene symbol:	Hnf1b
Gene name:	HNF1 homeobox B

Antibody:	anti-HNF1-beta (C-20): sc-7411
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

S2A WT ©

Specimen S2A WT: embryonic day 12.5 (more

)
Note: Controls were either wild type or heterozygous littermates.

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present		S2A WT

Specimen S2A Lats1/2/Yap1^PanKOTaz^Het: embryonic day 12.5; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0, Wwtr1^tm1.1Eno/Wwtr1⁺, Yap1^tm1.1Eno/Yap1^tm1.1Eno (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: pancreas	Present		S2A Lats1/2/Yap1^PanKOTaz^Het	Normal expression was detected in Lats1/2/Yap1<PanKO>Taz<Het> mice.

Specimen S2A Lats1/2^PanKO: embryonic day 15.5; Lats1^tm1.1Jfm/Lats1^tm1.1Jfm, Lats2^tm1.1Jfm/Lats2^tm1.1Jfm, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS23: pancreas	Present		S2A Lats1/2^PanKO

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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