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Gene Expression Data
Assay Details
Assay
Reference: J:375533 Ramzan M, et al., Carboxypeptidase D deficiency causes hearing loss amenable to treatment. J Clin Invest. 2025 Dec 1;135(23)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8293296
Gene symbol: Cpd
Gene name: carboxypeptidase D
Antibody: anti-CPD (PA5-103707)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1c: postnatal day 0 (more )
Note: Triple labeled: green - Cpd; magenta - Myo7a (assay MGI:8293297); red - Nefh (assay MGI:8293298).
Structure Cell Type Level Pattern Image Note
TS27: stria vascularis Present 1C left
TS27: organ of Corti cochlear inner hair cell Present 1C left , 1C right top
TS27: organ of Corti cochlear outer hair cell Present 1C left , 1C right top
TS27: cochlear ganglion Present 1C left , 1C right bottom
Specimen S4 P0 20x: postnatal day 0 (more )
Note: Triple labeled: green - Cpd; magenta - Myo7a (assay MGI:8293297); yellow - Nefh (assay MGI:8293298).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present S4_P0 Merge 20x , S4_P0 CPD 20x
TS27: organ of Corti cochlear outer hair cell Present S4_P0 Merge 20x , S4_P0 CPD 20x
Specimen S4 P0 60x: postnatal day 0 (more )
Note: Triple labeled: green - Cpd; magenta - Myo7a (assay MGI:8293297); yellow - Nefh (assay MGI:8293298).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present S4_P0 Merge 60x , S4_P0 CPD 60x
TS27: organ of Corti cochlear outer hair cell Present S4_P0 Merge 60x , S4_P0 CPD 60x
Specimen S4 P21 20x Organ of Corti: postnatal day 21 (more )
Note: Triple labeled: green - Cpd; red - Myo7a (assay MGI:8293297); white - Sox2 (assay MGI:8293299).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Present S4_P21 CPD 20x , S4_P21 Merge 20x
TS28: organ of Corti cochlear outer hair cell Present S4_P21 CPD 20x , S4_P21 Merge 20x
Specimen S4 P21 60x Organ of Corti: postnatal day 21 (more )
Note: Triple labeled: green - Cpd; red - Myo7a (assay MGI:8293297); white - Sox2 (assay MGI:8293299).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Present S4_P21 Merge 60x , S4_P21 CPD 60x
TS28: organ of Corti cochlear outer hair cell Present S4_P21 Merge 60x , S4_P21 CPD 60x
Specimen S4 P21 20x Spiral ganglia: postnatal day 21 (more )
Note: Triple labeled: green - Cpd; red - Myo7a (assay MGI:8293297); white - Sox2 (assay MGI:8293299).
Structure Level Pattern Image Note
TS28: cochlear ganglion Present S4_P21 Spiral g. CPD , S4_P21 Spiral g. Merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory