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Gene Expression Data
Assay Details
Assay
Reference: J:272613 Koutelou E, et al., USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8278760
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: Two Acta2 antibodies were listed; the one used in this assay was not specified. Either MGI:1314968 or MGI:5497006 could have been used.
Results
Specimen 1E WT: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: extraembryonic component pericyte Present Regionally restricted 1E WT ACTA2 Expression was detected in mural cells (pericytes) that surround the fetal endothelial cells in the placenta.
Specimen 1E Usp22-/-: embryonic day 12.5; Usp22Gt(RRS377)Byg/Usp22Gt(RRS377)Byg (more )
Structure Cell Type Level Pattern Image Note
TS20: extraembryonic component pericyte Present Regionally restricted 1E Usp22-/- ACTA2 Staining was misorganized in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
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