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Gene Expression Data
Assay Details
Assay
Reference: J:272613 Koutelou E, et al., USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8278757
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: Anti-Ki-67 (IHC-00375)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2B WT: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 2B WT KI67 Expression was detected in proliferating cells.

Specimen 2B Usp22-/-: embryonic day 9.0; Usp22Gt(RRS377)Byg/Usp22Gt(RRS377)Byg (more )
Structure Level Pattern Image Note
TS14: extraembryonic component Present Regionally restricted 2B Usp22-/- KI67 No marked change in proliferation was observed in E9 placental sections.

Specimen S7A WT: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: labyrinthine zone trophoblast cell Present Regionally restricted S7A WT KI67 Expression was detected in proliferating cells.

Specimen S7A Usp22-/-: embryonic day 12.5; Usp22Gt(RRS377)Byg/Usp22Gt(RRS377)Byg (more )
Structure Cell Type Level Pattern Image Note
TS20: labyrinthine zone trophoblast cell Weak Regionally restricted S7A Usp22-/- KI67 Usp22 mutant labyrinths show reduced proliferation of labyrinth trophoblasts at E12.5.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory